Alzheimer's disease can be treated: Why the delay?

Thousands of published papers have continued to report that amyloid deposition in the brain of Alzheimer disease (AD) patients is the basis for the disease. Two observations deserve attention. It has been found at autopsy that the percentage of amyloid plaques within the brains of nondemented, age‐adjusted individuals can be the same percentage of amyloid plaques found at autopsy within the brains of AD patients.[3] Another study found no relationship between the number of amyloid plaques located in the brains of AD patients and their degree of dementia severity.[36] These findings clearly challenge the presumption that the presence of amyloid in the AD brain is the basis for the disease.